For U.S. callers, you can call us at 1-800-338-5803 toll free or +1-201-262-8899 for international callers or you can email us at firstname.lastname@example.org.
You can order directly from Halocarbon.
It is stocked and sold by most veterinary distributors.
It is available in 100ml and 250ml bottles packed 6 bottles per case.
Worldwide usage of Halothane has been declining for years and continued production no longer made economic sense.
Please click on Material Safety Data Sheets on the Halocarbon web site for disposal information.
Yes. Contact us for a list of companies that perform this service.
Call G.A.S. at 1-800-717-5955 (U.S. only) or Southmedic at 1-800-463-7146 (U.S. and Canada).
We are working on next generation anesthetics.
Yes, Halocarbon manufactures its sevoflurane in its plant in South Carolina, USA. In addition, unlike other sevoflurane suppliers, Halocarbon is one of the world's largest manufacturers of the key precursor to sevoflurane, hexafluoroisopropanol (HFIP).
Yes, the US FDA has approved Halocarbon's sevoflurane as a therapeutic equivalent to Ultane® and lists Halocarbon's sevoflurane in their "Approved Drug Products with Therapeutic Equivalence Evaluations" (the "Orange Book").
Halocarbon's sevoflurane is packaged in 250 ml USP Type III amber glass containers with a water content of not more than 70 parts per million (ppm). In order to receive FDA approval, a drug's manufacturer must demonstrate its product's stability in the sale container. Data submitted to the FDA showed Halocarbon's sevoflurane in glass bottles was stable under standard accelerated conditions (bottles stored at 40ºC and 75% relative humidity for 3 months). Halocarbon also submitted data that showed its sevoflurane in glass bottles was stable under even more stressful hotter and drier conditions (60ºC and less than 5% relative humidity for 3 months). Halocarbon's stability testing and other research has produced no evidence that storing sevoflurane in type III glass results in Lewis Acid formation or otherwise contributes to decomposition of sevoflurane, or that the addition of water is necessary to promote stability.
Packaging is a matter of patents and/or marketing preference and each container type has its advantages and disadvantages. If a company has a compatible plastic container patented, obviously other manufacturers cannot use that type of packaging. While a glass bottle can break and an aluminum bottle can't, the sevoflurane level in the glass bottle is visible. Sevoflurane in plastic bottles has been recalled due to pinhole leaks in the plastic. As previously noted, in order to receive FDA approval, a drug must be shown to be stable in whatever container it is supplied.
No, other than company names.
Yes, Halocarbon's sevoflurane is listed by the FDA as a therapeutic equivalent to Ultane®.
As with all inhalation anesthetics, product handling, storage and administration information must be thoroughly reviewed prior to any use of drug. Please consult both the product insert and the MSDS.
Ultane® is a registered trademark of Abbott Laboratories, N. Chicago, IL.