Trifluoroacetyl Chloride - CF3COCl
CAS NO. 354-32-5
Trifluoroacetyl chloride, a gas at ambient conditions and sold as a liquid under pressure, provides a convenient way to introduce a trifluoromethyl group into complex organic molecules. It is used in the production of agricultural and pharmaceutical molecules.
When reacted with a compound containing active hydrogen it will yield a trifluoromethyl compound and hydrochloric acid as byproduct. Due to the electron withdrawing effect of CF3 group, the reactivity of the carbonyl group towards nucleophilic reagents is increased when compared to the non-fluorinated analogue.
When reacted with a compound containing active hydrogen it will yield a trifluoromethyl compound and hydrochloric acid as byproduct. Due to the electron withdrawing effect of CF3 group, the reactivity of the carbonyl group towards nucleophilic reagents is increased when compared to the non-fluorinated analogue.
| Specifications: | ||
| Assay by Gas Chromatography | 99.5% minimum | |
| Hydrolyzable Fluoride | 0.01% maximum | |
| Physical Properties: | ||
| Mol. Wt.: | 132.45 | |
| Boiling Pt: | -28°C | |
| Melting Pt: | -146°C | |
| Density: | 1.384 | |
| Vapor Pressure: | 72 psia (25°C) | |
| Appearance and Odor: | Colorless liquefied gas with pungent odor. | |
| Solubility in water: | Exothermic reaction with water to form water soluble trifluoroacetic acid and byproduct HCl. | |
| Packaging: | ||
| 100 kg and 890 kg cylinders | ||
| Bulk Containers | ||