TFE and its derivatives are prevalent in many pharmaceuticals and pharmaceutical intermediates. Halocarbon trifluoroethanol (TFE) and trifluoroethyl amine (TFEA) provide a straightforward means to introduce aliphatic trifluoro methyl-groups into APIs to produce fluorinated ethers, esters, amines, amides, or carbamates.

Trifluoroethanol Derivatives